Genetics and Epigenetics, the Future of Skin Care?

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The 28th European Democosmetology Days organized by the European Centre for Dermocosmetology (CED) in Lyon, France, on the 30th and 31st of January 2017 focused on personalized genomics and epigenetics, and how this could shape the future of dermocosmetology.

Skin changes are among the most visible signs of aging. Skin properties such as hydration, elasticity, and antioxidant capacity play a key role in the skin aging process. Skin aging is a complex process influenced by heritable and environmental factors.

Most of those environmental factors include nutrition, sleep, UVA exposure and pollution. Recent studies on twins have revealed that up to 60% of the skin aging variation between individuals can be attributed to genetic factors, while the remaining 40% is due to non-genetic factors. Recent advances in genomics and bioinformatics approaches have led to the association of certain single nucleotide polymorphisms (SNPs) to skin properties[1]. The epigenetic science studies the influence of the environment on the expression of genes without modifying the DNA sequence.

A few innovative companies are already making progress in identifying key relevant genetic markers, and selecting relevant skin markers. The combination of personalized facial serum, nutritional supplements, and life coaching brings the promise to age better.

[1] Clin Cosmet Investig Dermatol. 2014 Jul 1; 7:207-14. Doi: 10.2147/CCID.S55669. ECollection 2014. Genetic polymorphisms and skin aging: the identification of population genotypic groups holds potential for personalised treatments.

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